Outstanding facilities for undergraduate and graduate research are available on and off campus. The department is housed in three buildings: Castetter Hall, Marron Hall, and the Biology Department Annex. A full range of computer facilities are available for all students, faculty, and staff. The Milne Landscape Ecology Laboratory supports a computer facility for students and faculty who are researching relationships between spacial patterns and processes in ecological systems. Newly remodeled Molecular Biology Facility assists teaching and research for faculty, students and staff using state-of-the-art equipment for sequencing and synthesizing DNA.

The Watson respirometry lab is available to students interested in studying behavioral energetics in small to medium size creatures. Additional specialized laboratory facilities are found at the University Medical Center and the Lovelace Institute in Albuquerque. The Sevilleta LTER Field Station at the Sevilleta National Wildlife Refuge 80 km south of Albuquerque, includes housing as well as a laboratory and computer facility. A newly constructed research greenhouse was recently built with funds from the NSF. The Museum of Southwestern Biology has an excellent collection of plants, invertebrates, fish, amphibians, reptiles, birds and mammals. Students and faculty also conduct research at field sites throughout the Southwest and Rocky Mountain Region, and in the Gulf of California. Field projects are often undertaken even further afield, in Latin America, Australia, Africa, and the Antarctic.