Publications and Patents:

Journal Articles (in chronological order):

  D.Z. Chen, S. Luan and J. Xu. Topological peeling and applications. International Journal of Computational Geometry and Applications (IJCGA), Vol. 13, No. 2, April 2003, page 135-172.

  S. Luan, D.Z. Chen, L. Zhang, X. Wu, and C.X. Yu. An Optimal Algorithm for Computing Configuration Options of One-dimensional Intensity Modulated Beams. Physics in Medicine and Biology, Vol. 48, No. 15, August 2003, page 2321-2338.

  S. Luan, C. Wang, D.Z. Chen, X. S. Hu, S.A. Naqvi, C.L. Lee, and C.X. Yu. A new MLC segmentation algorithm/software for step-and-shoot IMRT delivery. Medical Physics, Vol. 31, No. 4, April 2004, page 695-707.

  D.Z. Chen, X. S. Hu, S. Luan, C. Wang, and X. Wu. Geometric Algorithms for Static Leaf Sequencing Problems in Radiation Therapy. International Journal of Computational Geometry and Applications (IJCGA), Vol. 14, October 2004, pp. 311-339.

  D.Z. Chen, X.S. Hu, S. Luan, X. Wu, and C.X. Yu. Optimal Terrain Construction Problems and its application in intensity modulated radiation therapy. Algorithmica, Vol. 42, No. 3-4, June 2005, pp. 265-288.

  D.Z. Chen, X.S. Hu, S. Luan, S.A. Naqvi, C. Wang, and C.X. Yu. Generalized Geometric Approaches for Leaf Sequencing Problems in Radiation Therapy. International Journal of Computational Geometry and Applications (IJCGA), Vol. 16, No 2-3, June 2006. 175-204.

  D. Cao, M. Earl, S Luan and D. Shepard. Continuous Intensity Map Optimization (CIMO): A Novel Approach to Leaf Sequencing in Step and Shoot IMRT. Medical Physics, Vol 33, No. 4, 2006, pages 859-867.

  S Luan, C. Wang, D.Z. Chen, X.S. Hu, S.A. Naqvi, X. Wu, and C.X. Yu. An improved MLC segmentation algorithm and software for step-and-shoot IMRT delivery without tongue-and-groove error. Medical Physics, Vol 33, No. 5, 2006 pages 1199-1212.

  C. Yu, D. Shepard, M. Earl, D. Cao, S Luan, C. Wang and D. Chen. New Developments in Intensity Modulated Radiation Therapy. Technology in Cancer Research and Treatment, 2006, 451-564.

  S Luan, J. Saia and M. Young. Approximation algorithms for minimizing segments in radiation therapy. Information Professing Letters, Vol. 101, 2007, 239-244.

  S Luan, C. Wang, D. Cao, D.Z. Chen, D.M. Shepard, and C.X. Yu. Leaf-sequencing for intensity-modulated arc therapy using graph algorithms, Medical Physics, Vol 35, No. 1, 2008, 61-69.

  D.Z. Chen, S.X. Hu, S. Luan, C. Wang, and X. Wu. Mountain Reduction, Block Matching, and Medical Applications, International Journal of Computational Geometry and Applications (IJCGA), Vol. 18, Nos. 1-2 (April 2008), 63-106.

  G. Tang, M.A. Earl, S. Luan, C. Wang, D. Cao, C.X. Yu, and S.A. Naqvi. Stochastic vs. deterministic kernel based superposition approaches for dose calculation of intensity-modulated arcs. Physics in Medicine and Biology, 53 (2008), 4733-4746.

  C. Wang, S. Luan, G. Tang, D. Chen, M. Earl, C. Yu. Arc-modulated Radiation Therapy (AMRT): a single-arc form of Intensity-Modulated Arc Therapy. Physics in Medicine and Biology. Vol 53, No. 22, Nov. 2008, pages 6291-6304.

  S. Luan, N. Swanson, and L. Ma. Dynamic Gamma Knife Radiosurgery, Physics in Medicine and Biology, 54 (2009), 1579-1591.

  G. Tang, M. Earl, S. Luan, C. Wang, S. Naqvi, M. Mohiuddin, and C. Yu. Comparing Radiation Treatments Using Intensity-Modulated Beams, Multiple Arcs and Single Arc. Accepted to International Journal of Radiation Oncology, Biology, Physics.

  D. Chen, S. Luan, C. Wang. Coupled Path Planning, Region Optimization, and Applications to Intensity-Modulated Raidiation Therapy. Accepted to Algorithmica, Special Issue of European Symposium of Algorithms (ESA¨2008).

  N. Bansal, D. Chen, X. Hu, S. Luan, E. Misiolek, B. Schieber, C. Wang. Shape Rectangularization Problems in Intensity-Modulated Radiation Therapy. Accepted to Algoirthmica.

Full Conference Articles (in chronological order):

  D.Z. Chen, S. Luan, and J. Xu. Topological peeling and implementation, in Springer-Verlag, Lecture Notes in Computer Science. Vol. 2223, Proc. 12th International Symposium on Algorithms and Computations (ISAAC), page 454-466, 2001.

  D.Z. Chen, S. Luan, and J. Xu. An Experimental Study and Comparison of Topological Peeling and Topological Walk. Lecture Notes in Computer Science, Vol. 2387, Springer Verlag, Proc. of the Eighth Annual International Computing and Combinatorics Conference (COCOON), Singapore, August 2002, page 456-466.

  D.Z. Chen, X.S. Hu, S. Luan, X. Wu, and C.X. Yu. Optimal Terrain Construction Problems and Applications in Intensity-Modulated Radiation Therapy. Lecture Notes in Computer Science, Vol.~2461, Springer Verlag, Proc. of the Tenth Annual European Symposium on Algorithms (ESA), Rome, Italy, September 2002, page 270-283.

  D.Z. Chen, X. S. Hu, S. Luan, C. Wang, and X. Wu. Geometric Algorithms for Static Leaf Sequencing Problems in Radiation Therapy. Proc. of 19th ACM Symposium on Computational Geometry (SoCG03), San Diego, CA, June 2003, page 88-97.

  D.Z. Chen, X.S. Hu, S. Luan, S.A. Naqvi, C. Wang, and C.X. Yu. Generalized Geometric Approaches for Leaf Sequencing Problems in Radiation Therapy. 15th International Symposium on Algorithms and Computation (ISAAC 2004), December 2004.

  D.Z. Chen, X.S. Hu, S. Luan, C. Wang, and X. Wu. Mountain Reduction, Block Matching, and Applications in Intensity-Modulated Radiation Therapy.  Proc. 21st ACM Symp. on Computational Geometry (SoCG¨05), pp. 35-44. Also, an invited submission to the International Journal of Computational Geometry and Applications (IJCGA).

  S. Luan, C. Wang, D.Z. Chen, and X.S. Hu. Leaf Sequencing Software for Intensity-Modulated Radiation Therapy. the 19th IEEE Symposium on Computer Based Software Systems, 2006.

  D.Z. Chen, X.S. Hu, S. Luan, E. Misiolek, and C. Wang. Shape Rectangularization Problems in Intensity-Modulated Radiation Therapy. 17th International Symposium on Algorithms and Computation (ISAAC¨06).

  D.Z. Chen, S. Luan and C. Wang. Coupled Path Planning, Region Optimization, and Applications in Intensity-Modulated Radiation Therapy. Proceedings of the 16th Annual European Symposium on Algorithms (ESA 2008).

Refereed Conference Abstracts (in chronological order):

  X. Wu, D.Z. Chen, X.S. Hu, S. Luan, L. Zhang, and C.X. Yu. A new leaf-sequencing algorithm for intensity-modulated arc therapy. Forty-Third Annual Meeting and Technical Exhibition of the American Association of Physicists in Medicine (AAPM), 2001.

  S. Luan, C. Wang, S.A. Naqvi, D.Z. Chen, X.S. Hu, C.L. Lee, and C.X. Yu. A New Leaf Sequencing Algorithm/Software for Step and Shoot IMRT. Forty-Fifth Annual Meeting and Technical Exhibition of the American Association of Physicists in Medicine (AAPM), 2003.

  S. Luan, C. Wang, D.Z. Chen, X.S. Hu, and C.X. Yu. A Study of the Impact of MLC Constraints on the Number of Segments in Step-and-Shoot IMRT Delivery. Forty-Sixth Annual Meeting and Technical Exhibition of the American Association of Physicists in Medicine (AAPM), 2004.

  S. Luan, C. Wang, D.Z. Chen, X.S. Hu, S.A. Naqvi, and C.X. Yu. A New MLC Segmentation Algorithm for Step and Shoot IMRT Without Tongue-and-Groove Error. Forty-Sixth Annual Meeting and Technical Exhibition of the American Association of Physicists in Medicine (AAPM), 2004.

  C. Wang, S. Luan, D.Z. Chen, X.S. Hu, and C.X. Yu. A Generalized MLC Segmentation Algorithm for Step-and-Shoot IMRT with no Tongue-and-Groove Error. The 47th Annual Meeting of American Association of Physicists in Medicine (AAPM), 2005.

  K.D. Roedersheimer, D.Z. Chen, S. Luan, and L. Xing. The Impact of Multileaf Collimator Rotation in IMRT Planning. The 47th Annual Meeting of the American Association of Physicists in Medicine (AAPM), 2005.

  S. Luan, P.H. Heintz, S.A. Sorensen, A.A. Jimenez, D.Z. Chen, K.D. Roedersheimer, G. Wong, The Effect of Collimator Rotation on IMRT Treatment Planning. The 47th Annual Meeting of American Society of Therapeutic Radiology and Oncology (ASTRO), 2005.

  D. Cao, M. Earl, S. Luan and D. Shepard. Continuous Intensity Map Optimization (CIMO): A Novel Leaf Sequencing Algorithm. 48th Annual Meeting of American Association of Physicists in Medicine (AAPM), 2006.

  S. Luan, C. Wang, D. Cao, D. Chen, W. D¨Souza, and C. Yu. Patient Breathing Motion Synchronized IMAT: A New Technique for Compensating Intra Fraction Organ Motions. The 48th Annual Meeting of American Association of Physicists in Medicine (AAPM), 2006.

  P. Wilkins, S. Luan, N. Swanson, P. Heintz, and L. Ketai. A New Algorithm/Software for CT Measurement of Airway Wall Volume. The Radiological Society of North America (RSNA) 92nd Scientific Assembly and Annual Meeting, 2006.

  S. Luan, N. Swanson, L. Ma, and K. Li, Dynamic Gamma Knife Radiosurgery, the 8th Bi-Annual Congress of International Society of Stereotactic Radiosurgery (ISRS¨2007).

  G. Tang, M. Earl, S. Luan, C. Wang, D.Z. Chen, S. Naqvi, and C.X. Yu. Comparison of intensity-modulated radiation therapy, intensity-modulated arc therapy, and arc modulated radiation therapy, the 50th Annual Meeting of American Association of Physicists in Medicine (AAPM), 2008.

  G. Tang, M. Earl, S. Luan, C. Wang, D.Z. Chen, and C.X. Yu. Is dose variation crucial for single-arc radiation therapy delivery, the 50th Annual Meeting of American Association of Physicists in Medicine (AAPM), 2008.

  C. Wang, S. Luan, G. Tang, M. Earl, D.Z. Chen, and C.X. Yu. Arc modulated radiation therapy, a novel method for rotational radiation therapy, the 50th Annual Meeting of American Association of Physicists in Medicine (AAPM), 2008.

  C. Wang, S. Luan, D.Z. Chen, G. Tang and C.X. Yu. Dynamic leaf sequencing with monitor unit control, the 50th Annual Meeting of American Association of Physicists in Medicine (AAPM), 2008.

  S. Luan, N. Swanson, Z. Chen, L. Ma. Treatment Planning for Dynamic Gamma Knife Radiosurgery. The 9th Bi-Annual Congress of International Society of Stereotactic Radiosurgery (ISRS¨2009).

  D. Cao, M. Rao, F. Chen, J. Ye, S. Luan, D. Shepard. A novel approach to machine specific QA for volumetric modulated arc therapy. The 51st Annual Meeting of American Association of Physicists in Medicine (AAPM), 2009.

  F. Chen, M. Rao, J. Ye, S. Luan, D. Shepard, D. Cao. Study of systemic and random errors on VMAT and IMRT plan quality and deliver accuracy. The 51st Annual Meeting of American Association of Physicists in Medicine (AAPM), 2009.

  B. Fahimian, J. DeMarco, R. Keyes, S. Luan, M. Zankl, M. Holzscheiter. Antiproton Radiotherapy: Development of Physically and Biologically Optimized Monte Carlo Treatment Planning Systems for Intensity and Energy Modulated Delivery. The 51st Annual Meeting of American Association of Physicists in Medicine (AAPM), 2009.

  R. Keyes, S. Luan, M. Holzscheiter. Antiproton Therapy: A simplified method to characterize and compare dose from peripheral radiation fields. The 51st Annual Meeting of American Association of Physicists in Medicine (AAPM), 2009.

  D. Riofrio, R. Keyes, A. Hecht, S. Luan, M. Holzscheiter, J. DeMarco, B. Fahimian. Planning Dynamic Particle Therapy. The 51st Annual Meeting of American Association of Physicists in Medicine (AAPM), 2009.

  L. Trestrail, D. Sanchez, D. Sandoval, P. Heintz, S. Luan, D. Chen. A Web-based Automated QA Analysis Program for Digital Image Tracking. The Radiological Society of North America (RSNA) 95th Scientific Assembly and Annual Meeting, 2009.

Patents:

  Inventor of US Patent 7.283,611 B1: Segmentation Algorithmic Approach to Step and-Shoot Intensity Modulated Radiation Therapy.

  Inventor of US Patent: 7,466,797: Error control in Algorithmic Approach to Step-and-Shoot Intensity Modulated Radiation Therapy.

  Co-Inventor of Single Arc Dose Painting: An efficient method of precision radiation therapy. International Patent Application Number: PCT/US08/005028 (Pending). (Licensed)

  Inventor of System and Method for using Dynamic Gamma Knife for Radiosurgery. PCT/US2009/002733 (Pending).

  Inventor of A method of Enhancing Photon Beam Focusing Power for Radiotherapy and Radiosurgery Delivery. Provisional Patent filed through UNM STC.