The Impact of Model Resolution on Antibody Aggregation Simulation

IgE antibodies bound to cell-surface receptors crosslink through antigen binding on the cell 
surface.  These aggregates induces allergic response, causing about 1500 American deaths per 
year.  Simulation of this process is critical to understanding allergic response.  However, 
this can be computationally expensive since the molecular structures are large.  We present a 
simulation technique that uses a simplified, polygon-based model that captures molecular 
structure and reduces computational cost.  We show the impact of model resolution on the 
simulation time and quality.