The Lakin Lab for Programmable Biology works on the modeling, design, and experimental implementation of biomolecular computers and synthetic gene networks, and on their practical application to biomedical problems such as autonomous nanomedicine and pathogen detection. We are interested in elucidating design rules for engineered biological and biomolecular systems, and in the development of scalable architectures for biomolecular computing. We use biological and bio-inspired approaches to implement behaviors such as adaptation and learning in engineered systems. We also work on the semantics and implementation of domain-specific declarative programming languages and software tools for biological modeling and biodesign. We are part of the Department of Computer Science, Department of Chemical & Biological Engineering, and Center for Biomedical Engineering at the University of New Mexico.
December 2021David's paper on implementing finite state automata using approximate majority reactions is published online in Royal Society Open Science. Congratulations!
December 2021Dr. Lakin is a co-author on a perspective piece arising from the SynCell2020/2021 conferences, now published online in eLife.
November 2021Dr. Caroline Rempe joins the group as a technical staff member working on outreach projects. Welcome!
September 2021Dr. Lakin is co-editor of the proceedings of the DNA27 conference, now available online.
August 2021Dr. Lakin gives an invited talk as part of the Build-A-Cell virtual seminar series.
August 2021A new undergraduate student, Sameen Jawadi, joins the group. Welcome!
August 2021Dr. Lakin is Co-PI on a newly awarded grant: NSF grant 2124308: Toward lifelike synthetic cells via engineered control of DNA replication.
August 2021Dr. Lakin's book chapter on applications of DNAzymes in nanotechnology is published by Wiley.
July 2021Dr. Lakin gives an invited talk at the Synthetic Approaches to Biology and Artificial Intelligence (SB-AI) workshop, a satellite workshop of the 2021 ALIFE conference.
July 2021Dr. Lakin is Co-PI on a newly awarded grant: NSF grant 2123465: Synthetic P-bodies: Coupling gene expression and ribonucleoprotein granules in synthetic cell vesicles for sensing and response.
June 2021Sarika's paper on structure sampling for tethered DNA nanostructures is published online in Scientific Reports. Congratulations!
May 2021Dr. Lakin gives an invited talk at the 2021 International Conference on Engineering Synthetic Cells and Organelles.
May 2021Dr. Lakin receives the UNM School of Engineering Junior Faculty Research Excellence award!
January 2021Dr. Lakin receives the NSF CAREER award! He is the PI of NSF grant 2044838: CAREER: Robust heterochiral molecular computing in mammalian cells. See the project website for more.
January 2021David's book chapter on nanoscale robotics is published by Wiley. Congratulations!
July 2020Dr. Lakin's review article on domain-specific languages for molecular computing is published online in ACS Synthetic Biology.
July 2020Tracy's paper on L-DNA molecular logic gates is published online in ACS Synthetic Biology. Congratulations!
June 2020Dr. Lakin is appointed as an Assistant Professor (by courtesy) in the UNM Department of Chemical & Biological Engineering.